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World leaders called for de-escalation in the Middle East after Iran's state media reported explosions in the central province of Isfahan on Friday and US media quoted officials saying Israel had carried out retaliatory strikes on its arch-rival. Iranian officials played down the incident and said the blasts caused no major damage. Israel had previously warned it would hit back after Iran fired hundreds of missiles and drones at Israel over the weekend. Follow our liveblog for the latest updates on the situation in the Middle East.